COVID-19 BRIEFING with updated information (06/09/2021) 

 

Vaccine Safety Updates/Information:

Please see this page for an updated FAQ on COVID vaccines in pregnancy written by our very own Dr. Watt! 

The New England Journal of Medicine published a report on the safety of mRNA COVID vaccines in pregnancy on April 21st, 2021. The study included >35,000 pregnant women and evaluated the risk of pregnancy-related adverse effects after receiving an mRNA COVID vaccine. Overall, the results were reassuring. You can read the full article here. Animal studies on the COVID vaccines have also shown no increase in safety concerns. This CDC page has additional information on safety and efficacy in pregnancy.

We support our pregnant and lactating patients and their choice to receive any of the available COVID vaccines. The American College of Ob/Gyn recommends vaccination of individuals who are actively trying to become pregnant or are contemplating pregnancy. It is not necessary to delay pregnancy after receiving vaccination.

 

Vaccine overview:
There are now three vaccines against Covid-19 available in the United States. All three have Emergency Use Authorization from the FDA. All vaccines have demonstrated high efficacy among their respective clinical trial endpoints.

  • They are not live virus vaccines and cannot cause COVID-19 infection.

  • The clinical trials on the safety and efficacy of the vaccines met the same high standards as with a typical vaccine approval process;  despite the rapid development of the COVID-19 vaccines, safety standards were not relaxed, in fact, additional safety monitoring systems have been used to track and monitor these vaccines.  

  • Safety data on their use in pregnancy do not indicate any safety concerns for mothers or their babies (over 100,000 pregnancies were reported to the CDC’s v-safe program as of April of 2021 with no evidence of any serious safety concerns).  For example, outcomes for vaccinated pregnant women and unvaccinated pregnant women were NO DIFFERENT for the following conditions:  miscarriage, stillbirth, gestational diabetes, pre-eclampsia, growth restriction, pre-term birth, and birth defects.

 

Pfizer and Moderna

These are mRNA vaccines.  They consist of mRNA encapsulated by a lipid nanoparticle.  They use the host cell’s machinery to make the coronavirus spike protein.  The spike protein then stimulates the host’s immune cells to make antibodies against COVID-19.

These are not live virus vaccines.

They cannot cause Covid infection.

They do not use an adjuvant to enhance vaccine efficacy.

They do not enter the nucleus of the host cell and cannot change the DNA (the genetic material) of the host cell.

They are 94-95% effective in preventing laboratory-confirmed COVID-19 illness.

 

J&J vaccine

The J&J vaccine is made from recombinant, replication-incompetent human adenovirus type 26 vector which encodes the SARS-CoV2 spike protein.

It is not a live virus vaccine.

It cannot cause Covid infection.

The adenovirus vector cannot replicate after administration.

The vaccine is rapidly cleared from tissues after injection.

It cannot alter the DNA (the genetic material) of the host cell.

It contains no preservatives.

Other adenovirus vector vaccines have been tested in pregnant women, including vaccines against HIV and Ebola, and have been found to be safe.

It is 66.9% effective in preventing severe Covid illness after one dose.

It is 93.1% effective in preventing hospitalization due to Covid illness.

 

In addition:
● Unfounded claims linking Covid-19 vaccines to infertility have been scientifically disproven.
● There is no need to avoid initiation or to discontinue breastfeeding in patients who receive the
Covid vaccines.

● We encourage our pregnant and lactating patients to register for the CDC's v-safe program if they choose to be vaccinated.


Whether our patients choose to be vaccinated or not, we strongly encourage everyone to continue with prevention measures such as wearing a mask, physical distancing, and hand washing.


These vaccines should not be administered within 14 days of receipt of another vaccine, such as TDaP, influenza or shingles. We strongly recommend our pregnant patients receive TDaP and influenza vaccines. Rhogam should be given at the appropriate times in pregnancy, regardless of when a Covid vaccine was given.


Enlarged axillary lymph nodes are a known side effect of the Covid vaccines. The Society of Breast Imaging recommends that one have screening mammograms performed before the administration of the vaccine or at least 4-6 weeks after the receipt of the last vaccine injection.

 

We do not have the vaccine available in our office, but will let you know if that does occur.

The following links may be helpful to make an appointment for a vaccine:
Vaccinefinder.org
https://covid19.colorado.gov/for-coloradans/vaccine/where-can-i-get-vaccinated
https://www.centura.org/covid-19

In addition, you may reference the following websites for the most up to date information:


Thank you again for your understanding in this unprecedented time. Please know that we care
about each of you and we want to keep everyone safe who comes into the office and protect our staff as well. If you have any questions or concerns, please don’t hesitate to call us at
303-795-0890.